Oskar Ryszard Lange (1904-1965)

"Oskar Blumenthal and the Lessing Theater in Berlin, 1888-1904"

Oskar Blumenthal (1852-1917) was Berlin’s most feared theatre critic in the early years of the new German Reich. He had the audacity of referring to Goethe as “an egghead” who had no understanding of what made plays effective for audiences, and in other critiques he ridiculed Kleist, Hebbel, and other “important” playwrights—prompting an adversary publicly to call him a “one-man lynch mob.” In ...

Oskar Lange and the influence of Walrasian theory during the Keynesian revolution

Localization of oskar RNA regulates oskar translation and requires Oskar protein.

The site of oskar RNA and protein localization within the oocyte determines where in the embryo primordial germ cells form and where the abdomen develops. Initiation of oskar RNA localization requires the activity of several genes. We show that ovaries mutant for any of these genes lack Oskar protein. Using various transgenic constructs we have determined that sequences required for oskar RNA l...

Karl Oskar Illmensee (1939?)

Karl Oskar Illmensee studied the cloning [2] and reproduction of fruit flies, mice, and humans [3] in the US and Europe during the twentieth and twenty-first centuries. Illmensee used nuclear transfer techniques (cloning [2]) to create early mouse [4] embryos from adult mouse [4] cells, a technique biologists used in later decades to help explain how embryonic cells function during development....

Dmd065755 1891..1904

The cytochrome P450 2C19 (CYP2C19) enzyme plays an important role in the metabolism of many commonly used drugs. Relatively little is known about CYP2C19 inhibitors, including compounds of natural origin, which could inhibit CYP2C19, potentially causing clinically relevant metabolism-based drug interactions. We evaluated a series (N = 49) of structurally related plant isoquinoline alkaloids for...